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#1 |
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Member
Join Date: Jan 2008
Location: Malta, ny, USA
Posts: 91
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Well I've been taking pain medication for a long time, it all start when i was out ridin my dirt bike in the pits in NY. hit a jump and ended up falling and messing my neck and back up. Then a few years later i was ridin bmx out in these nice 6pack near my moms house ended up coming up short on this jump hiting my front tire off the landing
dunno why i didnt bail but went head first into the ground. ended up in the hospital for the night with a neckbrace for the next month of so was out of work. And during all this i was on hydrocodone and loratab basicaly the same deal both for pain releif, its been about 2 years now but ive taken so many pain pills that im affraid that my kidneys are hurt from it, I currently take when my back does hurt oxycodone 10mg 325, it seems as tho the are the only thing to help with the pain, and not to say they get you a real good feeling in your body. Just wondering if people take pain medication daily and if i should worry about kidney failure, Im only 21 |
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#2 | ||
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Join Date: Feb 2006
Location: United States
Posts: 914
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-You're not supposed to use anti-inflammitories or pain relievers everyday..Run them in a cycle, thats why you use up your reccommended amount then go back to your doctor to assess your condition, and yes they are harmful to your body with continuous use..
-Talk to your doctor.. -As for me, I use ben-gay for an intercourse lube, works wonders...
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#3 | ||
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Senior Member
Join Date: Oct 2002
Location: Bay Area, CA, US
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If you have chronic pain I would suggest talking to your doctor about seeing a pain specialist. Quote:
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#4 | |||
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Join Date: Feb 2006
Location: United States
Posts: 914
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-SO in other words....Don't use it everyday..I'm pretty sure OxyConton or Vicadin is under a higher category supervision, and long continued use of any acetaminophen is found to cause kidney damage..Also with those two drugs, people become dependent w/o even knowing it... /thread
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#5 |
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Senior Member
Join Date: Oct 2002
Location: Bay Area, CA, US
Posts: 835
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Aleve? You mean naproxen? Is that why I got a 90 day supply sitting next to me with directions to take 2 times a day, BID, as needed for pain?
Please, please, take a pharmacology class before you start giving advise on meds. Better yet, become and MD or something. When you get that, maybe you will learn how to spell VICODIN, and how to give advice. /thread
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#6 |
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Senior Member
Join Date: Oct 2002
Location: Bay Area, CA, US
Posts: 835
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DAVIS'S Drug Guide for NURSES TENTH EDITION
High Alert hydrocodone (hye-droe-koe-done) Hycodan, Robidone, Tussigon (U.S. antitussive formulations contain homatropine) hydrocodone/acetaminophen Anexsia, Bancap HC, Ceta-Plus, Co-Gesic, Dolacet, Duocet, Hydrocet, Hydrogesic, Hy-Phen, Lorcet, Lortab, Margesic-H, Norco, Oncet, Panacet, Stagesic, T-Gesic, Vanacet, Vicodin, Zydone hydrocodone/aspirin Alor, Azdone, Damason-P, Lortab ASA, Panasal hydrocodone/ibuprofen Vicoprofen CLASSIFICATION(S) Therapeutic: allergy, cold, and cough remedies (antitussive), nonopioid analgesics , opioid analgesics Pharmacologic: opioid agonists/nonopioid analgesic combinations Schedule III (in combination) Pregnancy Category C (with acetaminophen, or ibuprofen) UK (aspirin) For information on the acetaminophen, aspirin, and ibuprofen components of these formulations, see the acetaminophen, aspirin, and ibuprofen monographs = Canadian drug name. INDICATIONS • Used mainly in combination with nonopioid analgesics (acetaminophen/aspirin/ibuprofen) in the management of moderate to severe pain • Antitussive (usually in combination products with decongestants) ACTION • Bind to opiate receptors in the CNS. Alter the perception of and response to painful stimuli while producing generalized CNS depression ○ Suppress the cough reflex via a direct central action • Therapeutic Effects: ○ Decrease in severity of moderate pain ○ Suppression of the cough reflex PHARMACOKINETICS Absorption: Well absorbed following oral administration Distribution: Unknown Metabolism and Excretion: Mostly metabolized by the liver Half-life: 3.8 hr TIME OF ACTION analgesic effect ROUTE ONSET PEAK DURATION PO 10-30 min 30-60 min 4-6 hr CONTRAINDICATIONS/PRECAUTIONS Contraindicated in: • Hypersensitivity to hydrocodone • Hypersensitivity to acetaminophen/aspirin/ibuprofen (for combination products) • Aspirin- and ibuprofen-containing products should be avoided in patients with bleeding disorders or thrombocytopenia • Acetaminophen should be avoided in patients with severe hepatic or renal disease • Pregnancy or lactation (avoid chronic use) • Products containing alcohol, aspartame, saccharin, sugar, or tartrazine (FDC yellow dye #5) should be avoided in patients who have hypersensitivity or intolerance to these compounds Use Cautiously in: • Head trauma • Increased intracranial pressure • Severe renal, hepatic, or pulmonary disease • Hypothyroidism • Adrenal insufficiency • Alcoholism • Geriatric or debilitated patients (initial dosage reduction required; more prone to CNS depression, constipation) • Patients with undiagnosed abdominal pain • Prostatic hypertrophy ADVERSE REACTIONS/SIDE EFFECTS* *CAPITALS indicate life threatening; underlines indicate most frequent. Noted for hydrocodone only; see acetaminophen/aspirin/ibuprofen monographs for specific information on individual components CNS: confusion, sedation, dysphoria, euphoria, floating feeling, hallucinations, headache, unusual dreams, EENT: blurred vision, diplopia, miosis, Resp: respiratory depression, CV: hypotension, bradycardia, GI: constipation, nausea, vomiting, GU: urinary retention, Derm: sweating, Misc: physical dependence, psychological dependence, tolerance, INTERACTIONS Drug-Drug: • Use with extreme caution in patients receiving MAO inhibitors (may produce severe, unpredictable reactions--reduce initial dose of hydrocodone to 25% of usual dose) • Additive CNS depression with alcohol, antihistamines , and sedative/hypnotics • Administration of partial antagonist opioids ( buprenorphine , butorphanol , nalbuphine , or pentazocine ) may precipitate opioid withdrawal in physically dependent patients • Buprenorphine or pentazocine may decrease analgesia Drug-Natural: • Concomitant use of kava, valerian, skullcap, chamomile, or hops can increase CNS depression ROUTE AND DOSAGE • PO (Adults ): Analgesic--2.5-10 mg q 3-6 hr as needed; if using combination products, acetaminophen or aspirin dosage should not exceed 4 g/day; Antitussive--5 mg q 4-6 hr as needed • PO (Children ): Analgesic--0.15-0.2 mg/kg q 3-6 hr AVAILABILITY Hydrocodone • Hydrocodone tablets: 5 mg (Hycodan) • Cost: $77.82/100 • Hydrocodone syrup: 5 mg/ml (Hycodan, Robidone) • Cost: $71.56/480 ml Hydrocodone/Acetaminophen • Tablets: 2.5 mg hydrocodone/500 mg acetaminophen (Lortab 2.5/500), 5 mg hydrocodone/400 mg acetaminophen (Zydone), 5 mg hydrocodone/500 mg acetaminophen (Anexsia 5/500, Co-Gesic, Dolacet, Hydrocet, HydrogesicHy-Phen, Lorcet, Lortab 5/500, Margesic -H, Panacet 5/500, Stagesic, T-Gesic,Vicodin,), 7.5 mg hydrocodone/400 mg acetaminophen(Zydone), 7.5 mg hydrocodone/500 mg acetaminophen (Lortab 7.5/500), 7.5 mg hydrocodone/650 mg acetaminophen (Anexsia 7.5/650, Lorcet Plus), , 7.5 mg hydrocodone/750 mg acetaminophen (Vicodin ES), 10 mg hydrocodone/325 mg acetaminophen(Norco), 10 mg hydrocodone/500 mg acetaminophen (Lortab 10/500), 10 mg hydrocodone/650 mg acetaminophen (Lorcet 10/650, Vicodin HP), 10 mg hydrocodone/660 mg acetaminophen (Anexia 10/660) • Cost: Lorcet-HD $40.94/100, Lorcet Plus $72.70/100, Lorcet 10/650 $111.82/100; Lortab 2.5/500 $77.82/100, Lortab 5/500 $64.20/100, Lortab 7.5/500 $77.82/100, Lortab 10/500 $72.84/100, Norco $68.23/100, Vicodin $52.23/100, Vicodin ES $60.24/100, Vicodin HP $78.84/100 • Capsules: 5 mg hydrocodone/500 mg acetaminophen ( Bancap-HC, Dolacet, Hydrocet, Hydrogesic, Lorcet-HD, Margesic-H, Stagesic, T-Gesic, Zydone) • Elixir/oral solution: 2.5 mg hydrocodone plus 167 mg acetaminophen/5 ml Hydrocodone/Aspirin • Tablets: 5 mg hydrocodone/500 mg aspirin (Azdone, Damason-P, Lortab ASA, Panasal 5/500) • In combination with: antihistamines, caffeine, guaifenesin, decongestants. See Appendix B Hydrocodone/Ibuprofen • Tablets: 7.5 mg hydrocodone/200 mg ibuprofen NURSING IMPLICATIONS ASSESSMENT • Assess blood pressure, pulse, and respirations before and periodically during administration. If respiratory rate is <10/min, assess level of sedation. Physical stimulation may be sufficient to prevent significant hypoventilation. Dose may need to be decreased by 25-50%. Initial drowsiness will diminish with continued use ○ Assess bowel function routinely. Prevention of constipation should be instituted with increased intake of fluids and bulk, and laxatives to minimize constipating effects. Stimulant laxatives should be administered routinely if opioid use exceeds 2-3 days, unless contraindicated • Pain: Assess type, location, and intensity of pain prior to and 1 hr (peak) following administration. When titrating opioid doses, increases of 25-50% should be administered until there is either a 50% reduction in the patient's pain rating on a numerical or visual analogue scale or the patient reports satisfactory pain relief. A repeat dose can be safely administered at the time of the peak if previous dose is ineffective and side effects are minimal ○ An equianalgesic chart (see Appendix B ) should be used when changing routes or when changing from one opioid to another ○ Prolonged use may lead to physical and psychological dependence and tolerance. This should not prevent patient from receiving adequate analgesia. Most patients who receive opioids for pain do not develop psychological dependence. If progressively higher doses are required, consider conversion to a stronger opioid • Cough: Assess cough and lung sounds during antitussive use • Lab Test Considerations: May cause increased plasma amylase and lipase concentrations • Toxicity and Overdose: If an opioid antagonist is required to reverse respiratory depression or coma, naloxone (Narcan) is the antidote. Dilute the 0.4-mg ampule of naloxone in 10 ml of 0.9% NaCl and administer 0.5 ml (0.02 mg) by direct IV push every 2 min. For children and patients weighing <40 kg, dilute 0.1 mg of naloxone in 10 ml of 0.9% NaCl for a concentration of 10 mcg/ml and administer 0.5 mcg/kg every 2 min. Titrate dose to avoid withdrawal, seizures, and severe pain POTENTIAL NURSING DIAGNOSES (visual, auditory) • Acute pain (Indications). • Disturbed sensory perception (visual, auditory) (Side Effects). • Risk for injury (Side Effects). IMPLEMENTATION • High Alert: Accidental overdosage of opioid analgesics has resulted in fatalities. Before administering, clarify all ambiguous orders; have second practitioner independently check original order and dose calculations. Do not confuse hydrocodone with hydrocortisone. Do not confuse Lortab with Lorabid (loracarbef) • Explain therapeutic value of medication prior to administration to enhance the analgesic effect ○ Regularly administered doses may be more effective than prn administration. Analgesic is more effective if given before pain becomes severe ○ Combination with nonopioid analgesics may have additive analgesic effects and permit lower doses. Maximum doses of nonopioid agents limit the titration of hydrocodone doses ○ Medication should be discontinued gradually after long-term use to prevent withdrawal symptoms • PO: May be administered with food or milk to minimize GI irritation PATIENT/FAMILY TEACHING • Advise patient to take medication exactly as directed and not to take more than the recommended amount. Severe and permanent liver damage may result from prolonged use or high doses of acetaminophen. Renal damage may occur with prolonged use of acetaminophen or aspirin. Doses of nonopioid agents should not exceed the maximum recommended daily dose • Instruct patient on how and when to ask for pain medication • May cause drowsiness or dizziness. Advise patient to call for assistance when ambulating or smoking. Caution patient to avoid driving or other activities requiring alertness until response to the medication is known • Advise patient to change positions slowly to minimize orthostatic hypotension • Caution patient to avoid concurrent use of alcohol or other CNS depressants with this medication • Encourage patient to turn, cough, and breathe deeply every 2 hr to prevent atelectasis • Advise patient that good oral hygiene, frequent mouth rinses, and sugarless gum or candy may decrease dry mouth EVALUATION/DESIRED OUTCOMES • Decrease in severity of pain without a significant alteration in level of consciousness or respiratory status • Suppression of nonproductive cough
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#7 |
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Senior Member
Join Date: Oct 2002
Location: Bay Area, CA, US
Posts: 835
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naproxen (na-prox-en) Aleve, Anaprox, Anaprox DS, Apo-Napro-Na, Apo-Napro-Na DS, Apo-Naproxen, EC-Naprosyn, Naprelan, Napron X, Naprosyn, Naprosyn-E, Naprosyn-SR, Naxen, Novo-Naprox, Novo-Naprox Sodium DS, Nu-Naprox, Synflex, Synflex DS CLASSIFICATION(S) Therapeutic: nonopioid analgesics , nonsteroidal anti-inflammatory agents, antipyretics Pregnancy Category B (first trimester) = Canadian drug name. INDICATIONS • Mild to moderate pain • Dysmenorrhea • Fever • Inflammatory disorders, including: ○ Rheumatoid arthritis (adults and children) ○ Osteoarthritis ACTION • Inhibits prostaglandin synthesis • Therapeutic Effects: ○ Decreased pain ○ Reduction of fever ○ Suppression of inflammation PHARMACOKINETICS Absorption: Completely absorbed from the GI tract. Sodium salt (Anaprox) is more rapidly absorbed Distribution: Crosses the placenta; enters breast milk in low concentrations Protein Binding: >99% Metabolism and Excretion: Mostly metabolized by the liver Half-life: Children < 8 yr: 8-17 hr; Children 8-14 yr: 8-10 hr; Adults: 10-20 hr TIME OF ACTION ROUTE ONSET PEAK DURATION PO (analgesic) 1 hr unknown 8-12 hr PO (anti-inflammatory) 14 days 2-4 wk unknown CONTRAINDICATIONS/PRECAUTIONS Contraindicated in: • Hypersensitivity • Cross-sensitivity may occur with other NSAIDs, including aspirin • Active GI bleeding • Ulcer disease • Lactation: Avoid use in third trimester of pregnancy; may cause premature closure of the ductus arteriosis. Passes into breast milk and should not be used by nursing mothers Use Cautiously in: • Severe cardiovascular, renal, or hepatic disease • History of ulcer disease or any other history of gastrointestinal bleeding (may increase the risk of GI bleeding) • Underlying cardiovascular disease (may increase the risk of MI or stroke) • Chronic alcohol use/abuse • Geri: Increased risk of adverse reactions • OB: Avoid using during third trimester of pregnancy • Pedi: Children <2 yr (safety not established) ADVERSE REACTIONS/SIDE EFFECTS* *CAPITALS indicate life threatening; underlines indicate most frequent. CNS: dizziness, drowsiness, headache, EENT: tinnitus, visual disturbances, Resp: dyspnea, CV: edema, palpitations, tachycardia, GI: DRUG-INDUCED HEPATITIS, GI BLEEDING, constipation, dyspepsia, nausea, anorexia, diarrhea, discomfort, flatulence, vomiting, GU: cystitis, hematuria, renal failure, Derm: photosensitivity, rashes, sweating, pseudoporphyria (12% incidence in children with juvenile rheumatoid arthritis -- discontinue therapy if this occurs), Hemat: blood dyscrasias, prolonged bleeding time, Misc: ALLERGIC REACTIONS INCLUDING ANAPHYLAXIS AND STEVENS-JOHNSON SYNDROME, INTERACTIONS Drug-Drug: • Concurrent use with aspirin decreases naproxen blood levels and may decrease effectiveness • Increased risk of bleeding with anticoagulants , thrombolytic agents , eptifibatide , tirofiban , cefotetan , cefoperazone , valproic acid , clopidogrel , and ticlopidine • Additive adverse GI side effects with aspirin , corticosteroids , and other NSAIDs • Probenecid increases blood levels and may increase toxicity • Increased risk of photosensitivity with other photosensitizing agents • May increase the risk of toxicity from methotrexate , antineoplastics , or radiation therapy • May increase serum levels and risk of toxicity from lithium • Increased risk of adverse renal effects with cyclosporine or chronic use of acetaminophen • May decrease response to ACE Inhibitors , angiotensin II antagonists, or furosemide • May increase risk of hypoglycemia with insulin or oral hypoglycemic agents Oral potassium supplements may increase GI adverse effects Drug-Natural: • Increased anticoagulant effect and bleeding risk with anise, arnica, chamomile, clove, dong quai, feverfew, garlic, ginger, ginkgo, Panax ginseng, licorice, and others ROUTE AND DOSAGE 275 mg naproxen sodium is equivalent to 250 mg naproxen Anti-inflammatory/Analgesic/Antidysmenorrheal • PO (Adults ): Naproxen--250-500 mg bid (up to 1.5 g/day). Delayed-release naproxen--375-500 mg twice daily.Naproxen sodium--275-550 mg twice daily (up to 1.65 g/day) • PO (Children >2 yr): Analgesia: 5-7 mg/kg/dose every 8-12 hr. Inflammatory disease: 10-15 mg/kg/day divided q 12 hr, maximum: 1000 mg/day Antigout • PO (Adults ): Naproxen--750 mg naproxen initially, then 250 mg q 8 hr. Naproxen sodium--825 mg initially, then 275 mg q 8 hr OTC Use (naproxen sodium) • PO (Adults ): 200 mg q 8-12 hr or 400 mg followed by 200 mg q 12 hr (not to exceed 600 mg/24 hr) • PO (Geriatric Patients >65 yr): Not to exceed 200 mg q 12 hr AVAILABILITY Naproxen • Tablets (Naprosyn, {Apo-Naproxen, Naxen, Novo-Naprox, Nu-Naprox}): 125 mg, 250 mg, 375 mg, 500 mg • Cost: 250 mg $83.72/100, 375 mg $110.76/100, 500 mg $135.20/100 • Controlled-release tablets (Naprelan): 375 mg, 500 mg • Delayed-release tablets (EC-Naprosyn, Naprosyn-E): 250 mg, 375 mg, 500 mg • Extended-release tablets (Naprosyn-SR): 750 mg • Oral suspension (Naprosyn): 125 mg/5 ml • Cost: 125 mg/5 ml $38.23/500 ml • Suppositories (Naprosyn, Naxen): 500 mg Naproxen Sodium • Tablets (Aleve, Anaprox, Anaprox DS, Apo-Napro-Na, Novo-Naprox Sodium, Novo-Naprox Sodium DS, Synaflex, Synaflex DS): 220 mgOTC, 275 mg, 550 mg • Cost: 275 mg $71.51/100, 550 mg $116.05/100 • In combination with: lansoprazole in a combination package (Prevacid NapraPac), pseudoephedrine (Aleve Cold and Sinus Tablets, Aleve Sinus and Headache Tablets). See Appendix B NURSING IMPLICATIONS ASSESSMENT • Patients who have asthma, aspirin-induced allergy, and nasal polyps are at increased risk for developing hypersensitivity reactions. Assess for rhinitis, asthma, and urticaria • Pain: Assess pain (note type, location, and intensity) prior to and 1-2 hr following administration • Arthritis: Assess pain and range of motion prior to and 1-2 hr following administration • Fever: Monitor temperature; note signs associated with fever (diaphoresis, tachycardia, malaise) • Lab Test Considerations: Evaluate BUN, serum creatinine, CBC, and liver function tests periodically in patients receiving prolonged therapy ○ May ↑ serum potassium, BUN, serum creatinine, alkaline phosphatase, LDH, AST, and ALT tests levels. May ↓ blood glucose, hemoglobin, and hematocrit concentrations, leukocyte and platelet counts, and CCr ○ Bleeding time may be prolonged up to 4 days following discontinuation of therapy ○ May alter test results for urine 5-HIAA and urine steroid determinations POTENTIAL NURSING DIAGNOSES • Acute pain (Indications). • Impaired physical mobility (Indications). IMPLEMENTATION • Administration in higher than recommended doses does not provide increased effectiveness but may cause increased side effects ○ Coadministration with opioid analgesics may have additive analgesic effects and may permit lower opioid doses ○ Analgesic is more effective if given before pain becomes severe • PO: For rapid initial effect, administer 30 min before or 2 hr after meals. May be administered with food, milk, or antacids to decrease GI irritation. Food slows but does not reduce the extent of absorption. Do not mix suspension with antacid or other liquid prior to administration • Dysmenorrhea: Administer as soon as possible after the onset of menses. Prophylactic treatment has not been shown to be effective PATIENT/FAMILY TEACHING • Advise patient to take this medication with a full glass of water and to remain in an upright position for 15-30 min after administration • Instruct patient to take medication as directed. Take missed doses as soon as remembered but not if almost time for the next dose. Do not double doses • May cause drowsiness or dizziness. Advise patient to avoid driving or other activities requiring alertness until response to the medication is known • Caution patient to avoid the concurrent use of alcohol, aspirin, acetaminophen, or other OTC medications without consulting health care professional. Use of naproxen with 3 or more glasses of alcohol per day may increase risk of GI bleeding • Advise patient to inform health care professional of medication regimen prior to treatment or surgery • Caution patient to wear sunscreen and protective clothing to prevent photosensitivity reactions (especially in children with JRA) • Instruct patients not to take OTC naproxen preparations for more than 3 days for fever and to consult health care professional if symptoms persist or worsen • Advise patient to consult health care professional if rash, itching, visual disturbances, tinnitus, weight gain, edema, black stools, persistent headache, or influenza-like syndrome (chills, fever, muscle aches, pain) occurs EVALUATION/DESIRED OUTCOMES • Relief of pain • Improved joint mobility. Partial arthritic relief is usually seen within 2 wk, but maximum effectiveness may require 2-4 wk of continuous therapy. Patients who do not respond to one NSAID may respond to another • Reduction of fever
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#8 |
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Senior Member
Join Date: Oct 2002
Location: Bay Area, CA, US
Posts: 835
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Any other medications you wish me to look up? You get some pretty cool programs when you go to nursing school like I did......
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#9 |
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Senior Member
Join Date: Oct 2004
Location: Santa Ana, CA
Posts: 1,408
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Lol, I have Davis's Drug guide sitting next to me. About to go to clinicals (The only reason I'm up at 5 in the morning) Damn nursing school.
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#10 | ||||
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Join Date: Feb 2006
Location: United States
Posts: 914
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-I too have a supply of naproxen, and mine says NO refills....Like i said, you have to go back to the doctor to get another supply, or take an OTC Aleve..Which I stated before tells you to discontinue use after 10 days.. -Im not refuting any of your pre-med claims on a copy and paste list of uses/drug names..And maybe in that two page paper of yours it says something about what the OP asked, but I don't see it.... Quote:
Modified by Mr. Giggles at 12:58 PM 10/6/2008 Modified by Mr. Giggles at 1:03 PM 10/6/2008
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#11 | |
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Senior Member
Join Date: Oct 2002
Location: Bay Area, CA, US
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The question was answered when I said-
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With that being said, you know what they say about arguing on the internet............
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#12 |
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Member
Join Date: Jan 2008
Location: Malta, ny, USA
Posts: 91
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for the most part i take them as the doctor would perscribe my girlfriend is a nurse so she knows all the stuff and i got all the books. I just have a real bad back problem and naproxen type dosnt really work, its like only narcotic pain pills work usally. The worst part i dont have health insurance to go get x-rays i looked into paying out of pocket but it came to over 3000.00 and i said screw that. I don't have a addiction to them cause i dont take em all the time, but i could easly see how it could hapen to people. well thanks
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#13 |
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Soul Sisters
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justhere4aday does
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#14 | |||
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Join Date: Feb 2006
Location: United States
Posts: 914
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